Facial Expressions Decoded in Mice

A combination of videography, machine learning, and brain imaging has identified facial expressions and neural activity patterns in mice that are associated with their emotions.

ruth williams
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

ABOVE: Six emotion-linked facial expressions of mice
JULIA KUHL

If a mouse is in a lot of pain, an experienced handler may see it in the animal’s facial expression—its narrowed eyes and bulging cheeks. But, subtler facial expressions may be more difficult to match to their moods. So researchers developed an unbiased machine learning approach to study hundreds of videos of mice and, as a result, have now catalogued a range of emotion-specific facial expressions. These expressions, the researchers show, can serve as handy readouts for studying the neural basis of emotions.

“It’s a tour de force in terms of techniques,” says neuroscientist Sheena Josselyn of the University of Toronto who was not involved in the research. “Using the techniques . . . they are really beginning to give [emotion] a scientific definition, which I think is really important.”

“The results provide an important advance by adding quantitative analysis of facial ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
Image of a woman in a microbiology lab whose hair is caught on fire from a Bunsen burner.
April 1, 2025, Issue 1

Bunsen Burners and Bad Hair Days

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

View this Issue
Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

sartorius logo
An illustration of PFAS bubbles in front of a blue sky with clouds.

PFAS: The Forever Chemicals

sartorius logo
Unlocking the Unattainable in Gene Construction

Unlocking the Unattainable in Gene Construction

dna-script-primarylogo-digital
Concept illustration of acoustic waves and ripples.

Comparing Analytical Solutions for High-Throughput Drug Discovery

sciex

Products

Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

Thermo Fisher Logo
Singleron Avatar

Singleron Biotechnologies and Hamilton Bonaduz AG Announce the Launch of Tensor to Advance Single Cell Sequencing Automation

Zymo Research Logo

Zymo Research Launches Research Grant to Empower Mapping the RNome

Magid Haddouchi, PhD, CCO

Cytosurge Appoints Magid Haddouchi as Chief Commercial Officer