Hungry Macrophages Keep Tattoos on Mice’s Skin

A new study reveals that a constant stream of ink-gobbling immune cells helps hold tattoos in place.

Written byDiana Kwon
| 2 min read

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PIXABAY, MBRAGION

Cycling macrophages that guzzle ink on the skin of mice help keep tattoos in place, according to a study published yesterday (March 6) in the Journal of Experimental Medicine.

This research “shows that tattoos are in fact much more dynamic than we previously had believed,” Johann Gudjonsson, a professor of immunology and dermatology at the University of Michigan who was not involved in the study, tells The New York Times.

The investigation began when a group of researchers in France, while examining the skin of black mice, discovered macrophages that consumed pigment particles after melanocytes, the cells that produced them, died.

To see if immune cells were also present in tattoos, the team inked the tails of albino mice and found that the macrophages were, ...

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  • Diana is a freelance science journalist who covers the life sciences, health, and academic life. She’s a regular contributor to The Scientist and her work has appeared in several other publications, including Scientific American, Knowable, and Quanta. Diana was a former intern at The Scientist and she holds a master’s degree in neuroscience from McGill University. She’s currently based in Berlin, Germany.

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