Cancer May Be Driven by DNA Outside of Chromosomes
Cancer May Be Driven by DNA Outside of Chromosomes
In the last decade, researchers have come to realize that tumors harbor bits of extrachromosomal DNA that can drive malignancy.
Cancer May Be Driven by DNA Outside of Chromosomes
Cancer May Be Driven by DNA Outside of Chromosomes

In the last decade, researchers have come to realize that tumors harbor bits of extrachromosomal DNA that can drive malignancy.

In the last decade, researchers have come to realize that tumors harbor bits of extrachromosomal DNA that can drive malignancy.

cancer genomics
Most Comprehensive Analysis of Cancer Genomes to Date
Most Comprehensive Analysis of Cancer Genomes to Date
Jef Akst | Feb 5, 2020
An interrogation of the whole genomes of more than 2,600 cancers yields clues about the genetic drivers of malignancy, how tumors evolve, and more.
MyHeritage Launches Health-Related Genetic Test, Ignites Debate
MyHeritage Launches Health-Related Genetic Test, Ignites Debate
Catherine Offord | Jul 9, 2019
Its screen for selected variants of some disease-linked genes gives customers an incomplete picture of their risk—do they know?
Genetically Personalized Fruit Flies Screen for Cancer Drugs
Genetically Personalized Fruit Flies Screen for Cancer Drugs
Ruth Williams | May 22, 2019
Fly avatars bearing multiple genetic changes akin to those of a cancer patient lead to a tailor-made treatment that has shrunk the patient’s tumors.
Q&A: A 10,000-Genome Milestone for Shared Pediatric Cancer Data  
Q&A: A 10,000-Genome Milestone for Shared Pediatric Cancer Data  
Carolyn Wilke | Apr 1, 2019
Computational biologist Jinghui Zhang of St. Jude realized scientists could work more efficiently with tools and genomic data shared on the cloud.
Hundreds of Inherited Gene Variants Contribute to Cancer
Hundreds of Inherited Gene Variants Contribute to Cancer
Abby Olena | Apr 5, 2018
In the largest study of its kind to date, researchers find more than 850 rare, heritable genetic alterations that can predispose humans to cancer.
Researchers Publish First Pan-Cancer Genomic Analyses in Pediatric Patients
Researchers Publish First Pan-Cancer Genomic Analyses in Pediatric Patients
Catherine Offord | Feb 28, 2018
Two large-scale studies reveal new insights into the genomic characteristics of childhood cancers.
Clarivate Ranks Most-Cited Researchers of 2017
Clarivate Ranks Most-Cited Researchers of 2017
Catherine Offord | Nov 15, 2017
China shows the biggest increase of any country in the number of scientists listed since last year, while cancer genomics emerges as one of the more dominant fields.
More than 18,000 Genomic Records from Cancer Patients Available
More than 18,000 Genomic Records from Cancer Patients Available
Kerry Grens | Jun 1, 2017
The publicly available database found nearly a third of samples included mutations targeted by either approved drugs or therapies in clinical trials. 
Angela Brooks: Splicing Specialist
Angela Brooks: Splicing Specialist
Diana Kwon | Apr 1, 2017
At the University of California, Santa Cruz, the researcher combs the cancer genome, looking for weaknesses.
Cancer Genomes
Cancer Genomes
The Scientist Staff | Mar 31, 2017
April Scientist to Watch Angela Brooks of the University of California, Santa Cruz, discusses her search to find vulnerabilities buried within the genomes of cancer cells.
AACR Q&A: Elaine Mardis
AACR Q&A: Elaine Mardis
The Scientist Staff | Apr 18, 2016
The genomics pioneer shares the sessions she most looks forward to at this year’s American Association for Cancer Research annual meeting.
Direct-to-Consumer Liquid Biopsy
Direct-to-Consumer Liquid Biopsy
Kerry Grens | Sep 13, 2015
Some doctors advise shoppers to be skeptical of a newly marketed cancer diagnostic.
Making Sense of the Tumor Exome
Making Sense of the Tumor Exome
Kerry Grens | May 18, 2014
An algorithm can pick out biologically and clinically meaningful variants from whole-exome sequences of tumors.
Watson Challenges Cancer
Watson Challenges Cancer
Kerry Grens | Mar 20, 2014
The IBM supercomputer, famous for its game show performance, will aid in cloud-based analyses of genomic data.  
Retracing Steps
Retracing Steps
Aimee Swartz | Nov 11, 2013
Sage Bionetworks aims to show that transparency and sharing are key to ensuring research reproducibility.
Bacterial DNA in Human Genomes
Bacterial DNA in Human Genomes
Ed Yong | Jun 20, 2013
A new study finds strong evidence that bacteria can transfer genes into human genomes, especially in cancer cells.
Identifying Spurious Cancer Mutations
Identifying Spurious Cancer Mutations
Dan Cossins | Jun 19, 2013
Researchers reveal why analyses of cancer-causing mutations are riddled with false positives and demonstrate a new approach that eliminates the problem.
Week in Review: April 8-12
Week in Review: April 8-12
Jef Akst | Apr 12, 2013
Hot topics from the AACR meeting; the ongoing debate about pesticides’ effects on bees; a treasure trove of baby dinos; conservation on social media