Wellcome Sanger Institute to Close Animal Facility
Wellcome Sanger Institute to Close Animal Facility
The move reflects scientists using more cell lines and organoids in genetic research, although some experts disagree with the decision to scale back the use of animal models.
Wellcome Sanger Institute to Close Animal Facility
Wellcome Sanger Institute to Close Animal Facility

The move reflects scientists using more cell lines and organoids in genetic research, although some experts disagree with the decision to scale back the use of animal models.

The move reflects scientists using more cell lines and organoids in genetic research, although some experts disagree with the decision to scale back the use of animal models.

cell line
HeLa Cells from Different Labs Vary in Genetics, Phenotype
HeLa Cells from Different Labs Vary in Genetics, Phenotype
Katarina Zimmer | Feb 26, 2019
This could account for some reproducibility problems in cell line research, according to the authors of a comprehensive analysis of HeLa variants.
Scientists Raise Concerns About Revisions to Human Research Regulations
Scientists Raise Concerns About Revisions to Human Research Regulations
Katarina Zimmer | Feb 19, 2019
Authors of a new paper take issue with revisions to regulations on biospecimen research enacted last month, and argue that cell lines should be treated differently from other biospecimens.
Image of the Day: Eye-Opener
Image of the Day: Eye-Opener
Sukanya Charuchandra | Jul 17, 2018
An open-source microscopy method can super-resolve live cells even under low lighting.
Roland Nardone, Advocate for Cell-Line Authentication, Dies
Roland Nardone, Advocate for Cell-Line Authentication, Dies
Kerry Grens | Jul 11, 2018
The Catholic University of America professor was also known for his summer workshops on the latest techniques.
One Way to Fix Reproducibility Problems: Train Scientists Better
One Way to Fix Reproducibility Problems: Train Scientists Better
Katarina Zimmer | Nov 28, 2017
Leonard Freedman, president of the Global Biological Standards Institute, discusses the causes of irreproducible science and his latest effort to spread best practices.
Papers Based on Misidentified Cell Lines Top 32,000
Papers Based on Misidentified Cell Lines Top 32,000
Kerry Grens | Oct 16, 2017
An analysis of contaminated literature finds that tens of thousands of papers used cell lines of questionable origins—and these were in turn cited by hundreds of thousands of other papers.
The Ever-Expanding T-Cell World: A Primer
The Ever-Expanding T-Cell World: A Primer
Ashley P. Taylor | Aug 7, 2017
Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer. The Scientist attempts to catalog them all.
New Resource for Banked iPSCs
New Resource for Banked iPSCs
Aggie Mika | May 11, 2017
Researchers describe hundreds of induced pluripotent stem cell lines from healthy individuals. 
Cell Lines Gain Cancer-Related Mutations
Cell Lines Gain Cancer-Related Mutations
Kerry Grens | Apr 27, 2017
A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.
Henrietta Lacks’s Family Seeks Compensation
Henrietta Lacks’s Family Seeks Compensation
Kerry Grens | Feb 15, 2017
Family members of Lacks, the donor behind the widely used HeLa cell line, are planning to sue Johns Hopkins University.
Popular Tumor Cell Line Contaminated
Popular Tumor Cell Line Contaminated
Kerry Grens | Aug 31, 2016
A commercially available glioblastoma cell line appears to be from a different source than its stated origins.
Scientists Skip Cell Line Validation
Scientists Skip Cell Line Validation
Kerry Grens | Oct 12, 2015
Despite known problems with contamination and mislabeled cell lines, most researchers continue to operate without authenticating cells’ identity.
The Great Big Clean-Up
The Great Big Clean-Up
Kerry Grens | Sep 1, 2015
From tossing out cross-contaminated cell lines to flagging genomic misnomers, a push is on to tidy up biomedical research.
Seeded by Weeds
Seeded by Weeds
K. John Morrow Jr. | May 1, 2015
More than 50 years after cross-contamination of cultured cell lines was recognized, the problem continues to plague the scientific community.
Know Thy Cells
Know Thy Cells
Jenny Rood | Apr 20, 2015
Nature journals will ask authors to authenticate cell lines used in manuscript submissions starting next month.
Top 10 Innovations 2014
Top 10 Innovations 2014
The Scientist Staff | Dec 1, 2014
The list of the year’s best new products contains both perennial winners and innovative newcomers.
Banking on iPSCs
Banking on iPSCs
Kerry Grens | Sep 1, 2014
A flurry of induced pluripotent stem cell banks are coming online, but they face significant business challenges.
Banking on iPSCs
Banking on iPSCs
Kerry Grens | Jun 29, 2014
A flurry of induced pluripotent stem cell banks are coming online, but they face significant business challenges.
Virus Detected in Human Cell Line
Virus Detected in Human Cell Line
Kerry Grens | Jun 4, 2014
A line of human fetal glial cells is infected with a human polyomavirus, researchers report.