ADVERTISEMENT
cartoon depiction of a pair of scissors about to cut a DNA double helix
Researchers Uncover New Families of Gene-Editing Enzymes
The results reveal evolutionary relatives of the Cas9 enzyme now used extensively in biotechnology.
Researchers Uncover New Families of Gene-Editing Enzymes
Researchers Uncover New Families of Gene-Editing Enzymes

The results reveal evolutionary relatives of the Cas9 enzyme now used extensively in biotechnology.

The results reveal evolutionary relatives of the Cas9 enzyme now used extensively in biotechnology.

genome editing
cartoon showing a hand taking a tool to a double-helix of DNA to represent gene editing
WHO Releases New Recommendations on Human Genome Editing
Annie Melchor | Jul 12, 2021 | 3 min read
The guidance comes after two years of consulting with hundreds of stakeholders, including indigenous peoples, religious leaders, patient groups, and scientists.
CRISPR, Cas-9, Nobel, Chemistry
CRISPR’s Adaptation to Genome Editing Earns Chemistry Nobel
Amanda Heidt | Oct 7, 2020 | 4 min read
Emmanuelle Charpentier and Jennifer Doudna reprogrammed the bacterial immune response into one of the most popular tools for genetics and molecular biology.
3D representation of a DNA helix and with a base offset from the main helix, illustrating the concept of base editing.
A CRISPR Alternative for Correcting Mutations That Sensitize Cells to DNA Damage
Deanna MacNeil, PhD | 3 min read
Researchers turned to base editors to correct mutations causing the rare genetic disease Fanconi anemia without inducing double-strand DNA breaks.
Panel Lays Out Guidelines for CRISPR-Edited Human Embryos
Lisa Winter | Sep 4, 2020 | 2 min read
The International Commission on the Clinical Use of Human Germline Genome Editing claims the technology is still too risky for therapeutic use.
crispr-cas9 duplications off-target effects insertions knock-ins
CRISPR Can Create Unwanted Duplications During Knock-ins
Katarina Zimmer | Feb 19, 2020 | 5 min read
A new study in mice documents frequent undesirable repeats of DNA insertions that are not detected using standard PCR analysis.
untitled-design
From Bench to Boardroom
Aparna Nathan | 5 min read
Taking inspiration from her PhD research, Ana Moreno formed a company where scientists use CRISPR to treat chronic pain
Ten Minute Sabbatical
The Scientist Staff | Jan 13, 2020 | 2 min read
Take a break from the bench to puzzle and peruse.
buri recombinetics hornell cow hereford bull polled genetically engineered talens gmo cattle livestock
Genome-Edited Hornless Cows’ Offspring Are Healthy: Study
Kerry Grens | Oct 9, 2019 | 2 min read
All six calves inherited the gene for preventing horn growth, but four also got a piece of the plasmid used to introduce the sequence to their dad—complicating regulatory approval.
Using Genetics and Genomics to Improve Food Security
The Scientist Creative Services Team | 1 min read
Pamela Ronald and Kan Wang will discuss how they enhance the yield and disease resistance of important crops.
crispr baby he jiankui gene editing genome fertility clinic emails
Fertility Clinics Sought Advice from Scientist Who CRISPRed Babies
Chia-Yi Hou | May 29, 2019 | 1 min read
Emails reveal that a facility in Dubai and others have asked geneticist He Jiankui for help in gene-editing embryos.
Scientist Forged Ethical Reviews for CRISPRed Babies
Kerry Grens | Jan 21, 2019 | 1 min read
He Jiankui could face charges after an investigation finds he used techniques prohibited in China to edit the genes of twin girls.
Laptop displays CRISPR poster.
The Next Generation of CRISPR-Cas Systems
Nathan Ni, PhD | 1 min read
Researchers reinvent genome editing with new CRISPR-Cas systems.
The Biggest Science News of 2018
Kerry Grens | Dec 27, 2018 | 7 min read
From disastrous scientific setbacks to the upending of scientific dogma and the end of a 40-year search for a protein
CRISPR Scientists Slam Methods Used on Gene-Edited Babies
Katarina Zimmer | Dec 4, 2018 | 6 min read
Since He Jiankui presented his results at last week’s gene editing summit, researchers have raised concerns about his protocol, calling the procedure “amateurish” and “unconscionable.”
CRISPR Biosensors for Disease Diagnostics
The Scientist Creative Services Team | 1 min read
Kiana Aran and Can Dincer will discuss potential advantages and diagnostic applications of CRISPR biosensing.
Opinion: Don’t Ban the Use of CRISPR in Embryos
John D. Loike | Nov 29, 2018 | 2 min read
Despite a premature and ethically sketchy claim of genome editing in twin girls, an outright prohibition could blunt promising, responsible progress.
Second CRISPR-Modified Pregnancy May Be Underway
Ashley P. Taylor | Nov 28, 2018 | 2 min read
He Jiankui, who reportedly edited the genomes of two babies already, broke the news at a conference in Hong Kong.
CRISPR Technologies for the New Era of Cell and Gene Therapy
The Scientist Creative Services Team | 1 min read
Experts will discuss how they use new CRISPR technologies to advance their cell and gene therapy research.
Claim of First Gene-Edited Babies Triggers Investigation
Catherine Offord | Nov 26, 2018 | 2 min read
He Jiankui says he has successfully used CRISPR-Cas9 to tweak the genes of twins born earlier this month. Some independent experts are dubious.
ADVERTISEMENT