Using bioinformatics, two teams of scientists identified inhibitory proteins for Cas9’s relative.

Two patients who received Sangamo’s zinc finger–based treatment for Hunter syndrome have lower biomarkers of the condition, but no signs of new enzyme production.

The Germany-based study will test an ex vivo genome-editing therapy for the inherited blood disorder β-thalassemia.

The results could lead to a treatment to lower cholesterol in patients with hypercholesterolemia.

Two studies find the genome-editing technique works best when cells have a faulty DNA-damage response that’s frequently present in cancers.  

Researchers have developed a variety of techniques to detect when CRISPR misses the mark.

Researchers identify antibodies for two commonly used Cas9 proteins in human blood. Investors take notice.

Fifty years ago, Arthur Kornberg announced to reporters that his team had synthesized functional DNA.

From single-cell analysis to whole-genome sequencing, this year's best new products shine on many levels.