genome editing

Researchers turned to base editors to correct mutations causing the rare genetic disease Fanconi anemia without inducing double-strand DNA breaks.

Taking inspiration from her PhD research, Ana Moreno formed a company where scientists use CRISPR to treat chronic pain

The results reveal evolutionary relatives of the Cas9 enzyme now used extensively in biotechnology.

The guidance comes after two years of consulting with hundreds of stakeholders, including indigenous peoples, religious leaders, patient groups, and scientists.

Emmanuelle Charpentier and Jennifer Doudna reprogrammed the bacterial immune response into one of the most popular tools for genetics and molecular biology.

The International Commission on the Clinical Use of Human Germline Genome Editing claims the technology is still too risky for therapeutic use.

A new study in mice documents frequent undesirable repeats of DNA insertions that are not detected using standard PCR analysis.

Take a break from the bench to puzzle and peruse.

All six calves inherited the gene for preventing horn growth, but four also got a piece of the plasmid used to introduce the sequence to their dad—complicating regulatory approval.

Emails reveal that a facility in Dubai and others have asked geneticist He Jiankui for help in gene-editing embryos.

He Jiankui could face charges after an investigation finds he used techniques prohibited in China to edit the genes of twin girls.

From disastrous scientific setbacks to the upending of scientific dogma and the end of a 40-year search for a protein

Since He Jiankui presented his results at last week’s gene editing summit, researchers have raised concerns about his protocol, calling the procedure “amateurish” and “unconscionable.”

Despite a premature and ethically sketchy claim of genome editing in twin girls, an outright prohibition could blunt promising, responsible progress.