From disastrous scientific setbacks to the upending of scientific dogma and the end of a 40-year search for a protein

Since He Jiankui presented his results at last week’s gene editing summit, researchers have raised concerns about his protocol, calling the procedure “amateurish” and “unconscionable.”

Despite a premature and ethically sketchy claim of genome editing in twin girls, an outright prohibition could blunt promising, responsible progress.

He Jiankui, who reportedly edited the genomes of two babies already, broke the news at a conference in Hong Kong.

He Jiankui says he has successfully used CRISPR-Cas9 to tweak the genes of twins born earlier this month. Some independent experts are dubious.

A mouse study details a method called VIVO that predicts the accuracy of any guide RNA.

Using bioinformatics, two teams of scientists identified inhibitory proteins for Cas9’s relative.

Two patients who received Sangamo’s zinc finger–based treatment for Hunter syndrome have lower biomarkers of the condition, but no signs of new enzyme production.

The Germany-based study will test an ex vivo genome-editing therapy for the inherited blood disorder β-thalassemia.