GPCR

Chemogenetics Doesn’t Work Like Many Thought
Kerry Grens | Aug 4, 2017
A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.
Discoverer of G Proteins Dies
Kerry Grens | Dec 29, 2015
Nobel laureate Alfred Gilman has passed away at age 74.
Flow Cytometry On-a-Chip
Jeffrey M. Perkel | Jun 1, 2015
Novel microfluidic devices give researchers new ways to count and sort single cells.
Identifying Antibodies that Target Membrane Proteins in Their Native Conformations
The Scientist Creative Services Team in collaboration with OXGENE | May 10, 2021
A new mammalian display platform enhances antibody discovery for challenging protein targets.
Light-Operated Drugs
Ruth Williams | Nov 1, 2014
Scientists create a photosensitive pharmaceutical to target a glutamate receptor.
Visualizing the Ocular Microbiome
Rina Shaikh-Lesko | May 12, 2014
Researchers are beginning to study in depth the largely uncharted territory of the eye’s microbial composition.
An Insoluble Problem?
Robert Michael Stroud | May 26, 2011
The challenges of crystallizing membrane proteins—and how they’re being overcome.
Bitter Pill
Richard P. Grant | Mar 1, 2011
Editor's choice in drug discovery