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Explore protein structure-function relationships with Site Saturation Variant Libraries

Improved Protein Engineering with a Synthetic Variant Library

Researchers use a directly-synthesized, near-complete variant library to avoid the limitations of error-prone PCR.

Improved Protein Engineering with a Synthetic Variant Library

Improved Protein Engineering with a Synthetic Variant Library

Researchers use a directly-synthesized, near-complete variant library to avoid the limitations of error-prone PCR.

Researchers use a directly-synthesized, near-complete variant library to avoid the limitations of error-prone PCR.

GPCR

Identifying Antibodies that Target Membrane Proteins in Their Native Conformations

The Scientist Creative Services Team in collaboration with OXGENE | May 10, 2021 | 2 min read

A new mammalian display platform enhances antibody discovery for challenging protein targets.

Chemogenetics Doesn’t Work Like Many Thought

Kerry Grens | Aug 4, 2017 | 3 min read

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

Discoverer of G Proteins Dies

Kerry Grens | Dec 29, 2015 | 1 min read

Nobel laureate Alfred Gilman has passed away at age 74.

Flow Cytometry On-a-Chip

Jeffrey M. Perkel | Jun 1, 2015 | 7 min read

Novel microfluidic devices give researchers new ways to count and sort single cells.

Light-Operated Drugs

Ruth Williams | Nov 1, 2014 | 2 min read

Scientists create a photosensitive pharmaceutical to target a glutamate receptor.

Visualizing the Ocular Microbiome

Rina Shaikh-Lesko | May 12, 2014 | 4 min read

Researchers are beginning to study in depth the largely uncharted territory of the eye’s microbial composition.

An Insoluble Problem?

Robert Michael Stroud | May 26, 2011 | 4 min read

The challenges of crystallizing membrane proteins—and how they’re being overcome.

Richard P. Grant | Mar 1, 2011 | 2 min read

Editor's choice in drug discovery

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