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Illustration of green fluorescent bacterial cells.
Cocaine Use Creates Feedback Loop with Gut Bacteria: Mouse Study
A jolt of norepinephrine in the mouse gut facilitates colonization by certain microbes, which in turn deplete glycine, enhancing cocaine-induced behaviors.
Cocaine Use Creates Feedback Loop with Gut Bacteria: Mouse Study
Cocaine Use Creates Feedback Loop with Gut Bacteria: Mouse Study

A jolt of norepinephrine in the mouse gut facilitates colonization by certain microbes, which in turn deplete glycine, enhancing cocaine-induced behaviors.

A jolt of norepinephrine in the mouse gut facilitates colonization by certain microbes, which in turn deplete glycine, enhancing cocaine-induced behaviors.

metabolomics
A pregnant figure is shaded in blue and outlined in blue, pink, and purple
Blood Biomarkers Predict the Onset of Labor: Study
Abby Olena, PhD | May 6, 2021 | 3 min read
Researchers integrated information from 45 protein, metabolite, and immune data points to identify a window two to four weeks before a pregnant person will go into labor.
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Distinct Microbiome and Metabolites Linked with Depression
Rachael Moeller Gorman | Dec 9, 2020 | 4 min read
The gastrointestinal tracts of people with major depressive disorder harbor a signature composition of viruses, bacteria, and their metabolic products, according to the most comprehensive genomic and metabolomic analysis in depression to date.
Learn How Multiomics Drives Biotherapeutic Discovery and Development
Advancing Biotherapeutics with Multiomics
The Scientist’s Creative Services Team and Tecan | 1 min read
Explore how biomolecular processes drive health and disease.
Nutrition Researchers Can Determine What You’ve Been Eating
Amber Dance | Dec 1, 2020 | 10+ min read
The study of diet, long plagued by inaccuracies in self reports, is entering a new age of precision with the methods of metabolomics.
Infographic: Deciphering Diet from Blood and Urine Samples
Amber Dance | Dec 1, 2020 | 1 min read
Nutrition researchers are beginning to use metabolomics to determine how healthy subjects’ diets are, and even to reveal specific properties of the foods they eat.
Discover the microbiome’s role in diabetes 
A Question of Balance: How the Gut Microbiome Influences Diabetes
The Scientist’s Creative Services Team | 1 min read
The presence of beneficial or detrimental microbes pulls the host toward health or disease.
How to Track Metabolites in Tissues Using NMR
Katherine Bourzac | Aug 1, 2018 | 7 min read
Whether it’s aligning software or prepping samples, researchers share their tips for studying the metabolome with this underused approach.
How Gaining and Losing Weight Affects the Body
Abby Olena, PhD | Jan 17, 2018 | 3 min read
Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.
Experimental Design and Sample Processing for Metabolomics
Experimental Design and Sample Processing for Metabolomics
The Scientist’s Creative Services Team | 1 min read
Shama Naz will discuss how controlling pre-analytical factors and selecting appropriate analytical tools improves the outcome of metabolomics experiments.
Metabolomics Data Under Scrutiny
Ashley P. Taylor | Sep 15, 2017 | 4 min read
Out of 25,000 features originally detected by metabolic profiling of E. coli, fewer than 1,000 represent unique metabolites, a study finds.
Altered Microbiome Contributes to Exaggerated Post-Diet Weight Regain in Mice
Tracy Vence | Nov 24, 2016 | 2 min read
Obesity-associated microbiome composition can persist after weight loss, affecting the exchange of metabolites between a mouse and its resident bugs, researchers report.
A person holding a section of his face and looking in to his brain through a magnifying glass stock illustration
Science Philosophy in a Flash - A Look at Aging Through Young Eyes 
Iris Kulbatski, PhD | 1 min read
Aimée Parker shares how her childlike curiosity and collaborative spirit motivate her scientific pursuits.
Top 10 Innovations 2015
The Scientist Staff | Dec 1, 2015 | 10+ min read
The newest life-science products making waves in labs and clinics
Brains vs. Biceps?
Rina Shaikh-Lesko | May 29, 2014 | 2 min read
Early humans may have made an evolutionary tradeoff, giving up muscular strength to fuel bigger brains.
Dogs under blanket together stock photo
A Nose by Any Other Name: Tracking the Scent of Tumor Metabolic Waste
Iris Kulbatski, PhD | 3 min read
The unique odor profiles of tumors can be used to develop diagnostic sensing tools.
Biomarkers Predict Future Cognitive Impairment
Tracy Vence | Mar 9, 2014 | 3 min read
A blood test can predict whether an asymptomatic older adult will develop cognitive impairment or Alzheimer’s disease within two to three years, a study shows.
More than Water
Erin Weeks | Sep 6, 2013 | 1 min read
A comprehensive analysis of human urine identifies more than 3,000 metabolites. 
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Metabolomic Links Between Environmental Exposures and Human Health
The Scientist’s Creative Services Team | 1 min read
Experts discuss how untargeted metabolomic studies connect environmental factors with human disease.
Next Generation: Smoking Out Cancer
Sabrina Richards | Jul 17, 2013 | 3 min read
Researchers analyze smoke generated during surgical tumor removal to distinguish healthy and diseased tissues in real time.
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