The Common Mouth Microbe That Keeps Popping Up in Tumors

Lab studies link the oral bacteria Fusobacterium nucleatum to cancers from the gut to the head and neck. Could targeting the microbe tackle tumors?

David Adam
| 6 min read
black-and-white image of an open mouth
Register for free to listen to this article
Listen with Speechify
0:00
6:00
Share

Might brushing your teeth protect against cancer? The suggestion looks like it belongs in the pages of an unreliable tabloid, but scientific evidence for the link is strong and growing.

Take head and neck cancer, which kills some 450,000 people worldwide every year. It’s associated with smoking and drinking alcohol, which is one reason why the most common form of the disease, oral squamous cell carcinoma (OSCC), tends to cluster in under resourced areas. But plenty of people diagnosed with OSCC say they never drank nor smoked, so researchers have been looking for other possible causes.

One likely candidate is gum disease. A series of studies have identified periodontitis, a bacterial infection that eats away soft tissue and eventually bone around teeth, as a risk factor for OSCC. That might be because the disease changes the behavior of usually benign bugs that live in the mouth.

A study published late ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • David Adam

    David Adam

    This person does not yet have a bio.
Share
Image of a woman in a microbiology lab whose hair is caught on fire from a Bunsen burner.
April 1, 2025, Issue 1

Bunsen Burners and Bad Hair Days

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

View this Issue
Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

sartorius logo
An illustration of PFAS bubbles in front of a blue sky with clouds.

PFAS: The Forever Chemicals

sartorius logo
Unlocking the Unattainable in Gene Construction

Unlocking the Unattainable in Gene Construction

dna-script-primarylogo-digital
Concept illustration of acoustic waves and ripples.

Comparing Analytical Solutions for High-Throughput Drug Discovery

sciex

Products

Atelerix

Atelerix signs exclusive agreement with MineBio to establish distribution channel for non-cryogenic cell preservation solutions in China

Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

Thermo Fisher Logo
Singleron Avatar

Singleron Biotechnologies and Hamilton Bonaduz AG Announce the Launch of Tensor to Advance Single Cell Sequencing Automation

Zymo Research Logo

Zymo Research Launches Research Grant to Empower Mapping the RNome