Freeze-Dried Mouse Sperm Sent by Postcard Produces Baby Mice

Rather than relying on samples that need to be shipped in glass vials and on ice, researchers have developed a new method that allows mouse sperm to be sent easily at room temperature using standard mail delivery.

amanda heidt
| 4 min read
One hand holds a white envelope with a blue and red striped border, while a second hand places a clear sheet of plastic inside with small squares of paper on it

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ABOVE: By freeze-drying mouse sperm on weighing paper and sandwiching the paper between protective plastic sheets, researchers were able to successfully mail the samples between labs in Japan.
DAIYU ITO, UNIVERSITY OF YAMANASHI

With mouse models undergirding so much scientific research, scientists have a vested interest in developing techniques to safely store and transport sperm samples between labs. Currently, most methods rely on shipping sperm in glass vials packed on dry ice, but glass is both heavy—raising the cost of shipping—and prone to breakage. In addition, any delays in shipping can result in thawed and unusable samples. In search of a better option, a team of scientists in Japan recently sent mouse sperm that was freeze-dried onto simple weighing paper and stored between two plastic sheets by postcard roughly 200 kilometers, from Kyoto to Yamanashi, where the rehydrated sperm fertilized eggs and produced healthy baby mice.

Their new method, detailed in ...

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Meet the Author

  • amanda heidt

    Amanda Heidt

    Amanda was an associate editor at The Scientist, where she oversaw the Scientist to Watch, Foundations, and Short Lit columns. When not editing, she produced original reporting for the magazine and website. Amanda has a master's in marine science from Moss Landing Marine Laboratories and a master's in science communication from UC Santa Cruz.
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