Researchers treat mice with retinitis pigmentosa using a gene therapy that reduces cone loss.
Researchers used gene therapy to treat mice with retinitis pigmentosa, a condition where there is progressive degeneration of photoreceptors in the retina caused by lack of gene expression in any of over 80 genes. They administered the CX3CL1 gene and found that treatment prolonged the survival of cones.
S.K. Wang et al., “Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa,” PNAS, doi:10.1073/pnas.1901787116, 2019.
A reimagined lipid vehicle for nucleic acids could overcome the limitations of current vectors.
View this Issue
In this webinar, Ethan Shelkey and Aurita Menezes will highlight key aspects in the design of cell-based assays.
Discover how alternative animal models provide new perspectives on physiological and biochemical processes.
Experts from the Women’s Brain Foundation and bit.bio will explore the importance of sex-specific in vitro models for neurological research and drug discovery.
Discover how scientists are designing the next groundbreaking vaccines against infectious diseases.
Multiomics platform streamlines workflows and provides real-time insights, optimizing resource usage and ensuring smooth, data-driven operations
Learn how to overcome the challenges of viral transduction workflows.
Inventia Life Science, an innovator in 3D cell culture technologies, announces the launch of RASTRUM™ Allegro, a groundbreaking advancement in 3D cell culture technology designed to accelerate drug discovery and disease research with unprecedented scalability, reproducibility, and efficiency.
Learn how a target enrichment approach improves the discovery and characterization of viral pathogens.
