Intelligence Gathering

Disease eradication in the 21st century

Written byMary Beth Aberlin
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

ANDRZEJ KRAUZETo get an idea of the terrible dread that polio used to evoke in your parents or grandparents, read the opening chapter of Nemesis, Philip Roth’s aptly named 2010 novel set in 1944 in a steamy Newark, New Jersey, neighborhood. Roth’s outbreak is fictional, but ever since the first US polio epidemic in June 1916, summer’s arrival came with the fear of infection, and parents often limited whom their children could play with and where they were allowed to go.

And that dread was not an overreaction. Although sporadic polio outbreaks occurred every summer, 1952 saw the worst epidemic in the United States, with almost 58,000 reported cases. Of those, 3,145 people died and 21,269 suffered paralysis ranging from mild to disabling. The development of the Salk vaccine three years later, followed by the introduction of an oral vaccine, turned polio from a frightening nemesis to a disease virtually eradicated in industrialized countries.

Polio and guinea worm disease are on the brink of total eradication.

But worldwide, the picture was vastly different. In 1988, when an initiative was launched to stamp out polio worldwide, 1,000 children around the globe were crippled by the infection every day. Epidemiologists and public-health workers set out with the firm ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here
Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

fujirebio logo

Products

Eppendorf Logo

Research on rewiring neural circuit in fruit flies wins 2025 Eppendorf & Science Prize

Evident Logo

EVIDENT's New FLUOVIEW FV5000 Redefines the Boundaries of Confocal and Multiphoton Imaging

Evident Logo

EVIDENT Launches Sixth Annual Image of the Year Contest

10x Genomics Logo

10x Genomics Launches the Next Generation of Chromium Flex to Empower Scientists to Massively Scale Single Cell Research