Decoy Cells Trick SARS-CoV-2, Reduce Cytokines In Vitro
Decoy Cells Trick SARS-CoV-2, Reduce Cytokines In Vitro
Genetically engineered cells that overproduce ACE2, the receptor the novel coronavirus uses to enter cells, neutralize infection in vitro and mop up inflammatory cytokines in mice.
Decoy Cells Trick SARS-CoV-2, Reduce Cytokines In Vitro
Decoy Cells Trick SARS-CoV-2, Reduce Cytokines In Vitro

Genetically engineered cells that overproduce ACE2, the receptor the novel coronavirus uses to enter cells, neutralize infection in vitro and mop up inflammatory cytokines in mice.

Genetically engineered cells that overproduce ACE2, the receptor the novel coronavirus uses to enter cells, neutralize infection in vitro and mop up inflammatory cytokines in mice.

cytokines
T Cells and Neurons Talk to Each Other
T Cells and Neurons Talk to Each Other
Ashley Yeager | Oct 1, 2020
Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.
The Brain’s Immune Cells Stand Sentinel Against Viral Invasion
The Brain’s Immune Cells Stand Sentinel Against Viral Invasion
Ashley Yeager | Oct 1, 2020
Some viruses, possibly even SARS-CoV-2, can sneak into the brain through the nose. Recent studies show that microglia are ready for them when they do.
Infographic: How Cytokines Flow into and out of the Brain
Infographic: How Cytokines Flow into and out of the Brain
Ashley Yeager | Oct 1, 2020
Several routes exist for immune cells to communicate with neurons in the central nervous system, though T cells rarely come in direct contact with neural tissue.
p53 as an Immune System Modulator in Cancer
p53 as an Immune System Modulator in Cancer
The Scientist Creative Services Team | Sep 25, 2020
Best known as a cell cycle regulator, p53 signaling mediates pro and anti-cancer immune responses as well
Special Report
The Immune Hallmarks of Severe COVID-19
The Immune Hallmarks of Severe COVID-19
Katarina Zimmer | Sep 16, 2020
Researchers are trying to make sense of immune systems gone haywire and develop biomarkers to predict who will become the sickest from a coronavirus infection.
Immune Cell and Its Cytokine Control Exploratory Behavior in Mice
Immune Cell and Its Cytokine Control Exploratory Behavior in Mice
Ashley Yeager | Sep 14, 2020
Gamma delta T cells in the meninges of the brain release a cell signaling molecule that does more than protect mice from microbial pathogens.
Blood Replacement Rescues Mice from Stroke Damage
Blood Replacement Rescues Mice from Stroke Damage
Amanda Heidt | Aug 31, 2020
When mice that had suffered a stroke were given blood from a healthy donor, they experienced less tissue and neurological damage.
Is a Bradykinin Storm Brewing in COVID-19?
Is a Bradykinin Storm Brewing in COVID-19?
Alakananda Dasgupta | Aug 26, 2020
Excess of the inflammatory molecule bradykinin may explain the fluid build-up in the lungs of patients with coronavirus infections. Clinical trials of inhibitors are putting this hypothesis to the test.
Infographic: SARS-CoV-2 Interferes with Bradykinin Regulation
Infographic: SARS-CoV-2 Interferes with Bradykinin Regulation
Alakananda Dasgupta | Aug 26, 2020
The leaky blood vessels and lung fluid build-up in some COVID-19 patients might be explained by the virus’s corruption of an inflammation safeguard.