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A white mouse sits in a Petri dish against a blue background.
A Neural Thermostat Sets the Intensity of Immune Responses
Specialized neurons in the brainstem and vagus nerve provide potential therapeutic targets for treating inflammatory disorders.
A Neural Thermostat Sets the Intensity of Immune Responses
A Neural Thermostat Sets the Intensity of Immune Responses

Specialized neurons in the brainstem and vagus nerve provide potential therapeutic targets for treating inflammatory disorders.

Specialized neurons in the brainstem and vagus nerve provide potential therapeutic targets for treating inflammatory disorders.

cytokines

Grey cloud of smoke on a black background.
After the Smoke Clears: Scars on the Immune System 
Danielle Gerhard, PhD | Apr 15, 2024 | 6 min read
Smoking leaves epigenetic marks on DNA long after cessation, with consequences for adaptive immunity.
Shielding From Allergies: It’s Not Just About Microbes
Mariella Bodemeier Loayza Careaga, PhD | Feb 7, 2024 | 4 min read
Clean and dirty mice respond similarly to allergens, challenging the idea that reduced microbial exposure is the primary cause behind the uptick in allergies.
Reporter Cell Line Development and Optimization for High Throughput Screening 
Reporter Cell Line Development and Optimization for High Throughput Screening 
The Scientist Staff | 1 min read
In this webinar, Junguk Park and Vanda Lopes will discuss luciferase-based reporter cell lines that assess cytokine signaling, GPCR signaling, and enzyme activity.
Surface rendering of microscopy image showing two dendritic cells (green) communicating with a nociceptor neuron (violet).
How Cells in the Skin Team Up To Fight Pathogens
Rachael Moeller Gorman | Apr 12, 2023 | 4 min read
Immune cells and pain neurons form complex partnerships to protect our bodies from pathogens, new research reveals.
T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
An illustration of cells growing in the presence of cytokines.
Advancing Immunotherapy Development with High-Quality Cytokines
The Scientist and Sino Biological | 3 min read
Superior quality cytokines are crucial for reliable research results and the safe production of cancer cell therapies.
Closeup of a pair of hands in blue gloves holding a white mouse and injecting it with an amber colored liquid.
Opioids Recruit the Immune System to Cause Withdrawal Symptoms
Dan Robitzski | Jan 25, 2023 | 6 min read
A study finds that T cells induced by heroin cross the blood-brain barrier to wreak havoc on the brain, hinting at new ways to prevent withdrawal.
three black mice lined up next to each other. the one on the left, fed a low-fat diet, has one small bald patch, the middle mouse, fed fish oil, has a large bald spot across its shoulders and back, and the right mouse, fed cocoa butter, has no baldness.
Fish Oil in Diet Can Cause Hair Loss in Mice, Study Finds
Katherine Irving | Jan 19, 2023 | 3 min read
The oil’s omega-3 fatty acids accumulate in the mice’s skin, triggering an immune response that causes hair loss.
A 96-well plate with wells spelling out “ANIMAL COMPONENT FREE”.  
Animal Component-Free Reagents Unleash Cell Culture’s True Potential 
The Scientist and MilliporeSigma | 3 min read
The latest synthetic and chemical reagents offer researchers more flexibility, stability, and consistency when working with their cells.
an immune cell in blood
Why Viral Infections Are More Severe in People with Down Syndrome
Andy Carstens | Oct 14, 2022 | 6 min read
In people with the genetic condition, inflammation can cause a mild infection to snowball out of control, a study finds.
A small, brown mouse runs on a narrow, miniature treadmill
How Exercise Helps Mice Fight Pancreatic Cancer
Dan Robitzski | Jun 15, 2022 | 5 min read
A study reveals a molecular pathway linking exercise to an amped-up immune response to pancreatic cancer and greater responsiveness to treatment.
Why Automation Is a Necessity for Clinical Diagnostics
Bringing Fluency to Clinical Diagnostics Through Automation 
Tecan | 1 min read
Automated liquid handling workstations offer flexibility for a wide range of application and process needs.
hands of a person checking their blood glucose level with a monitor
Growing Evidence Ties COVID-19 to Diabetes Risk
Bianca Nogrady | May 3, 2022 | 7 min read
Studies suggest SARS-CoV-2 infection could trigger the development of diabetes in some people, even those with no other risk factors.
illustration of people of different genders and races
Does Biological Sex Influence COVID-19 Outcomes?
Annie Melchor | Nov 2, 2021 | 10 min read
It’s unclear whether differing odds of dying between men and women reflect inherent differences between male and female immune systems or differences rooted in gender norms.
Scalable and reproducible solutions in CAR T cell therapy workflows 
Advancing CAR T Cell Research and Development
Bio-Rad | 1 min read
How to develop the best CAR T cell product for preclinical use.
A close-up of a fruit fly head with antenna clearly visible in front of its red eyes
Bacterial Infections Disrupt Flies’ Sense of Smell
Abby Olena, PhD | Jul 21, 2021 | 4 min read
The temporary loss of olfaction stops the flies from eating any more of whatever it is that made them sick.
Conceptual illustration of cells releasing cytokines in various shades of blue
Spleen-to-Liver Signals Control Systemic Inflammation
Ruth Williams | Apr 29, 2021 | 3 min read
In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger.
Learn How the Immune System Can Be Trained to Overcome Food Allergies
Retraining the Immune System Cavalry for Food Allergen Peacekeeping Missions
The Scientist | 1 min read
Explore food allergy immunotherapy for reversing patient symptoms.
Key Genes Related to Severe COVID-19 Infection Identified
Max Kozlov | Dec 14, 2020 | 3 min read
Differences in the expression of genes associated with antiviral immunity and lung inflammation may contribute to a more serious COVID-19 infection.
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