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A karyotype of chromosomes mostly stained blue with one stained red and green
Researchers Fuse Mouse Chromosomes in Scientific First
The findings will likely help elucidate the effects of chromosome fusions, which can cause disease but have also contributed to evolution.
Researchers Fuse Mouse Chromosomes in Scientific First
Researchers Fuse Mouse Chromosomes in Scientific First

The findings will likely help elucidate the effects of chromosome fusions, which can cause disease but have also contributed to evolution.

The findings will likely help elucidate the effects of chromosome fusions, which can cause disease but have also contributed to evolution.

PCR
A bright, illuminated, yellow cluster of spheres, representing a mutated base pair, stands out from a double helix of deep red base pairs joined by blue hydrogen bonds
Study: Sickle Cell Mutation Driven by Pressure, Not Random Chance
Dan Robitzski | Mar 17, 2022 | 6 min read
New research finds that the appearance of the HbS mutation, which protects against malaria but leads to sickle cell disease when present in two copies, was more common in sperm samples from men in Ghana, where malaria risk is high, than Europeans.
Illustration of man receiving a COVID test.
Opinion: What COVID-19 Has Taught Us About the Importance of Testing
Mark Kessel | Feb 1, 2022 | 5 min read
The pandemic has yielded many lessons. One is that adequate and well-distributed diagnostics are key to battling disease outbreaks.
Scientist working in a biosafety cabinet
Cell Culture Conquests: Finding and Defeating the Invisible Enemy
The Scientist’s Creative Services Team and MilliporeSigma | 3 min read
Cutting-edge reagents, kits, and techniques provide a robust solution to cell culture mycoplasma contamination.
Man in black suit looking at camera
Pioneering Geneticist C. Thomas Caskey Dies at 83
Natalia Mesa, PhD | Jan 28, 2022 | 3 min read
Caskey’s contributions to the field were instrumental to modern genetics.
two women wearing plastic gloves hold up hand-sized air-capture devices in a wooded area.
Scientists ID Dozens of Plants, Animals from Free-Floating DNA
Dan Robitzski | Jan 6, 2022 | 8 min read
In a trio of studies, researchers report capturing and analyzing airborne environmental DNA from a wide variety of plants and animals, suggesting a new way of monitoring which terrestrial species are present in an area.
stock photo
Cooking up the Perfect PCR Reaction
MilliporeSigma | 1 min read
Discover how to obtain optimal PCR results by selecting the right DNA polymerase and optimizing the reaction buffer.
The Researchers Who Pivoted to COVID-19: One Year On
Shawna Williams | Jul 1, 2021 | 7 min read
The Scientist checks in on scientists who switched gears to combat the pandemic.
Special report
a hand in a blue glove holds a clear plastic multiwell plate in a laboratory with foil-wrapped plates on a metal shelf in the background
Labs Worldwide Still Struggling Amid Broken Supply Chains
Katarina Zimmer | May 21, 2021 | 8 min read
Countries outside the US and Europe that are already used to long wait times for laboratory supplies are facing greater research disruptions than ever during the pandemic.
Discover how to avoid PCR inhibition
Crude Samples, Optimal Results
The Scientist’s Creative Services Team and MilliporeSigma | 1 min read
Discover how to avoid the PCR inhibitors that lurk in most nucleic acid samples.
a person in a white lab coat with a blue glove inserting a clear pcr tube into a which thermocycler while holding an orange box
Coronavirus Mutations Could Muddle COVID-19 PCR Tests
Jack J. Lee | May 17, 2021 | 4 min read
Researchers find that SARS-CoV-2 variants can evade primer-probe sets and recommend that diagnostic assays include multiple targets for reliability.
liquid-containing tube labeled Laboratory Test Wastewater Sample SARS-CoV-2
Sewage Sampling Robots Speed SARS-CoV-2 Detection
Ruth Williams | May 1, 2021 | 3 min read
An automated wastewater monitoring technique could enable researchers to predict outbreaks of the virus up to a week in advance.
Cartoon rendering of a PCR reaction
Five Key Components for a Successful PCR
MilliporeSigma | 1 min read
Fixing a PCR might be as simple as adjusting a component or two
Infographic: How to Ferret Out SARS-CoV-2 in Sewage
Ruth Williams | May 1, 2021 | 1 min read
Researchers use magnetic nanoparticles and liquid-handling robots in an effort to detect COVID-19 outbreaks early.
Dr. Brock standing in nature, holding a walking stick and wearing binoculars around his neck.
Microbiologist Thomas Brock Dies at 94
Lisa Winter | Apr 23, 2021 | 2 min read
Brock’s discovery of a thermophile bacteria at Yellowstone National Park in 1966 eventually enabled the development of PCR.
Millipore stock
Viral Nucleic Acid Purification in a Single Spin
The Scientist’s Creative Services Team and MilliporeSigma | 3 min read
A simple nucleic acid extraction approach quickly purifies genomic viral RNA and DNA while minimizing cross-contamination risks.
rugby, concussion, brain injury, concussion, trauma, saliva, spit, test, noninvasive, diagnostic, microRNA, small noncoding RNA, PCR, RNA
Simple Spit Test Could Diagnose Concussions
Asher Jones | Mar 24, 2021 | 2 min read
A noninvasive saliva test accurately identified concussions in a study of hundreds of rugby players.
Breastmilk Harbors Antibodies to SARS-CoV-2
Ashley Yeager | Nov 17, 2020 | 5 min read
An abundance of immunoglobulin antibodies, and a paucity of viral RNA, in breastmilk offer evidence that women can safely continue breastfeeding during the pandemic.
Quick and Reliable Plant DNA Extraction
Quick and Reliable Plant DNA Extraction
MilliporeSigma | 1 min read
An innovative, environmentally-friendly spin kit maximizes DNA isolation.
Toward COVID-19 Testing Any Time, Anywhere
Abby Olena, PhD | Sep 2, 2020 | 7 min read
Researchers are adapting CRISPR, synthetic biology, and other creative approaches to detect SARS-CoV-2 nucleic acids outside of the lab or doctors’ offices, in the hopes of making diagnostics more affordable and accessible.
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