Heart Attack Elevates Risk of Breast Cancer Recurrence: Study

Mice that experienced heart attacks underwent a large-scale shift in their immune systems that allowed cancer to flourish, perhaps explaining the observation in patients.

amanda heidt
| 4 min read
breast cancer, cardiovascular disease, heart attack, chemotherapy, cancer, cancer risk, women's health, oncology

Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

ABOVE: © ISTOCK.COM, ANDRESR

A couple of years ago, Kathryn Moore, the director of the Cardiovascular Research Center at NYU Langone Health, came across a study that made her pause. Researchers had tracked the cardiovascular outcomes of breast cancer patients and found that among women with only one or two risk factors—such as family history, hypertension, or diabetes—30 percent experienced a cardiovascular event, a troubling statistic that jumped to 50 percent among women with three or four risk factors. Given how frequent these events were, “I wondered whether having a heart attack affected their cancer,” says Moore, “and I was surprised to find that no one had looked at this.”

Research has long supported a link between cancer treatments such as chemotherapy that can weaken the heart and subsequent cardiovascular disease in patients. The effectiveness of modern treatments means “patients are living longer, but they’re also experiencing complications,” says Moore, ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • amanda heidt

    Amanda Heidt

    Amanda was an associate editor at The Scientist, where she oversaw the Scientist to Watch, Foundations, and Short Lit columns. When not editing, she produced original reporting for the magazine and website. Amanda has a master's in marine science from Moss Landing Marine Laboratories and a master's in science communication from UC Santa Cruz.
Share
May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
iStock

TaqMan Probe & Assays: Unveil What's Possible Together

Thermo Fisher Logo
Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Unchained Labs
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Thermo Fisher Logo

Products

fujirebio-square-logo

Fujirebio Receives Marketing Clearance for Lumipulse® G pTau 217/ β-Amyloid 1-42 Plasma Ratio In-Vitro Diagnostic Test

The Scientist Placeholder Image

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Leica Microsystems Logo

Latest AI software simplifies image analysis and speeds up insights for scientists

BioSkryb Genomics Logo

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours