Identifying a Killer, 1895

A contaminated ham put bacteriologist Émile Pierre-Marie van Ermengem on the path to discovering the microbe that produces botulinum toxin.

Written byCatherine Offord
| 4 min read
two black-and-white microscope images, one with a few black dots, the other with many rod-shaped bacteria

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On December 14, 1895, more than 30 brass band musicians sat down to dinner at a pub in the Belgian village of Ellezelles. They’d just played at a funeral, and, as was tradition, had gone to Le Rustic for a meat-heavy meal, complete with a large quantity of smoked and pickled ham. Within 24 hours, almost all of them fell sick with stomach problems, blurred vision, speech difficulties, and even paralysis. A week later, three had died and ten more were critically ill.

Suspicion quickly fell on the ham—musicians who hadn’t eaten it seemed unharmed—and local officials launched a full investigation, including interviews with survivors and background checks on the meat’s origins. Local medics would have suspected botulism, also known as “sausage poisoning,” says Frank Erbguth, a clinical neurologist at Paracelsus Medical University in Nuremberg who has studied the history of the condition. Associated with consumption of certain types of ...

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Meet the Author

  • After undergraduate research with spiders at the University of Oxford and graduate research with ants at Princeton University, Catherine left arthropods and academia to become a science journalist. She has worked in various guises at The Scientist since 2016. As Senior Editor, she wrote articles for the online and print publications, and edited the magazine’s Notebook, Careers, and Bio Business sections. She reports on subjects ranging from cellular and molecular biology to research misconduct and science policy. Find more of her work at her website.

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