December 2016

Traffic Cops

The structure and function of nuclear pores

Features

The Pangenome: Are Single Reference Genomes Dead?

Top 10 Innovations 2016

Contributors

Contributors

Editorial

Doors and Pores

Speaking of Science

Notable Science Quotes

Notebook

Birds Have Skills Previously Described as “Uniquely Human”

Elephant Footprints Create Habitat for Tiny Aquatic Creatures

Freshwater Bacteria Might Help Explain the “Methane Paradox”

Missing Link in Malaria Evolution Discovered in Historical Specimens

Critic at Large

Opinion: Not All Genetic Databases Are Equal

The Literature

Distantly Related Conifers Share a Surprising Number of Cold-Tolerance Genes

Studies Conflict on Spores’ Need for Protein Synthesis

Cells Follow Stiffness Gradients by Playing Tug-of-War

Profiles

Pushing Boundaries

Scientist to Watch

Vlad Denic on Exploring New Fields and Failing Successfully

Lab Tools

Using Raman Spectroscopy to Identify Cell Types

How to Track Cell Lineages As They Develop

Bio Business

Oligonucleotide Therapeutics Near Approval

Reading Frames

Is Medicine Ready for Clinical CRISPR?

Foundations

Early 3-D Image Analysis Revealed Surprising Symmetry in the Nuclear Pore

Modus Operandi

Synthetic Sensors

Cover Story

Nuclear Pores Come into Sharper Focus

Image of small blue creatures called Nergals. Some have hearts above their heads, which signify friendship. There is one Nergal who is sneezing and losing health, which is denoted by minus one signs floating around it.
June 2025, Issue 1

Nergal Networks: Where Friendship Meets Infection

A citizen science game explores how social choices and networks can influence how an illness moves through a population.

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An illustration of green lentiviral particles.

Maximizing Lentivirus Recovery

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Unraveling Complex Biology with Advanced Multiomics Technology

Unraveling Complex Biology with Five-Dimensional Multiomics

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Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Twist Bio 
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Seeing and Sorting with Confidence

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Products

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Waters Enhances Alliance iS HPLC System Software, Setting a New Standard for End-to-End Traceability and Data Integrity 

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Agilent Unveils the Next Generation in LC-Mass Detection: The InfinityLab Pro iQ Series

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Agilent Announces the Enhanced 8850 Gas Chromatograph

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Pioneering Cancer Plasticity Atlas will help Predict Response to Cancer Therapies