December 2016

Traffic Cops

The structure and function of nuclear pores

Features

The Pangenome: Are Single Reference Genomes Dead?

Top 10 Innovations 2016

Contributors

Contributors

Editorial

Doors and Pores

Speaking of Science

Notable Science Quotes

Notebook

Missing Link in Malaria Evolution Discovered in Historical Specimens

Birds Have Skills Previously Described as “Uniquely Human”

Elephant Footprints Create Habitat for Tiny Aquatic Creatures

Freshwater Bacteria Might Help Explain the “Methane Paradox”

Critic at Large

Opinion: Not All Genetic Databases Are Equal

Modus Operandi

Synthetic Sensors

Cover Story

Nuclear Pores Come into Sharper Focus

The Literature

Cells Follow Stiffness Gradients by Playing Tug-of-War

Distantly Related Conifers Share a Surprising Number of Cold-Tolerance Genes

Studies Conflict on Spores’ Need for Protein Synthesis

Profiles

Pushing Boundaries

Scientist to Watch

Vlad Denic on Exploring New Fields and Failing Successfully

Lab Tools

How to Track Cell Lineages As They Develop

Using Raman Spectroscopy to Identify Cell Types

Bio Business

Oligonucleotide Therapeutics Near Approval

Reading Frames

Is Medicine Ready for Clinical CRISPR?

Foundations

Early 3-D Image Analysis Revealed Surprising Symmetry in the Nuclear Pore

Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

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Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

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Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina

Products

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Nuclera eProtein Discovery System installed at leading Universities in Taiwan

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BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

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Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

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Thermo Scientific X and S Series General Purpose Centrifuges

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