Vitamin D on Trial

Prevention trials for vitamins and supplements are notoriously difficult, but some researchers aren’t giving up on finding proof that vitamin D helps ward off disease.

Written byAmy Maxmen
| 15 min read

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HARRY CAMPBELL

Once a month for the next 5 years, 20,000 people across the United States will find a package containing 62 pills in their mailboxes. As participants in a clinical trial, the recipients agreed to swallow two of the pills daily. But inevitably as the years pass, some pill packets will become buried under a stack of letters, or forgotten in a drawer. After all, these pills contain only vitamin D, fish oil, or an inert placebo—a person doesn’t need them to make it through the day. Plus, no one monitors who takes the pills daily and who does not.

In another study, 871 pregnant women swallow a vitamin D or a placebo pill every day for the duration of their pregnancy. Then every year for ...

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