Study Questions Sterility of Snake and Spider Venoms

In work that has not yet been peer-reviewed, researchers present evidence that microbes can and do live inside the venom glands of several dangerous species. It remains unclear whether they’re to blame for infections linked to bites.

Written byChristie Wilcox, PhD
| 8 min read
a vial of cobra venom next two two agar plates with visible microbial colonies on them
Register for free to listen to this article
Listen with Speechify
0:00
8:00
Share

Update (May 31): The paper described in this article was published May 23 in Microbiology Spectrum.

For years, researchers have been looking to animal venoms for the next generation of antibiotics. That’s because these chemical cocktails possess potent antimicrobial activities in addition to their dangerous physiological ones—a fact that has also led to the widespread idea that, despite being connected to the outside world, venom glands are sterile environments.

That’s simply not true, posits a November 5 biorXiv preprint. As the title neatly summarizes, “Microbial adaptation to venom is common in snakes and spiders.”

The research was led by Northumbria University RNA biologist Sterghios Moschos and venomologist Steve Trim, founder of the biotechnology company Venomtech, which aims to develop venom-based research tools and pharmaceuticals. It provides genetic and culture evidence that bacteria not only live in the venoms of several species of spiders and snakes, but are actively adapting to ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies