CRISPR Patent Ruling Favors Broad Institute

The US Patent and Trademark Office has once again decided that the institute has priority over the University of California and collaborators regarding intellectual property rights for CRISPR-Cas9 gene editing in eukaryotes. But the fight over the technique isn’t over.

Written byJef Akst
| 3 min read
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The US Patent and Trademark Office yesterday (February 28) ruled that the Broad Institute of MIT and Harvard will retain its intellectual property over the use of CRISPR-Cas9 gene editing in eukaryotes. While the University of California, the University of Vienna, and Emmanuel Charpentier (collectively known as the CVC group in legal filings) maintain their original patent over the use of CRISPR-Cas9 to edit genes in vitro and in prokaryotes and some other intellectual property pertaining to the technology, the ruling in this latest proceeding effectively invalidates filings that specifically covered use in eukaryotes, potentially forcing companies that have licensed the technology from the CVC group to negotiate new deals with the Broad or other stakeholders. The ruling is the latest twist in the battle for ownership of a technique being explored commercially for everything from crop improvement to treating genetic diseases.

The new ruling finds that, “in the eukaryotic ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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